Hydralazine is an oral and injectable drug that’s used to treat high blood pressure. It’s used alone or in combination with other blood pressure-lowering drugs. Common side effects include headache, loss of appetite, nausea, vomiting, diarrhea, fast heart rate, and chest pain. Don’t stop taking hydralazine suddenly.
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Does hydralazine cause weight loss?
Hydralazine is one of the most common drugs implicated in Drug-induced Systemic Lupus Erythematosus (DILE). Symptoms may occur anywhere from three weeks to two years after taking hydralazine and include rash, fever, weight loss, fatigue, joint or muscle pain, and kidney inflammation.
Who should not take hydralazine?
You should not use hydralazine if you are allergic to it, or if you have: coronary artery disease; or. rheumatic heart disease affecting the mitral valve.
What are the most common side effects of hydralazine?
- flushing.
- headache.
- upset stomach.
- vomiting.
- loss of appetite.
- diarrhea.
- constipation.
- eye tearing.
What happens if you take too much hydralazine?
If too much hydralazine is taken, get medical attention or call a poison control center. Although there are no known fatalities, an overdose can cause shock or serious heart problems such as heart attack. Symptoms of an overdose include flushing, headache, low blood pressure, and rapid heartbeat.
Does hydralazine cause depression?
Guanethidine, clonidine, hydralazine, and prazosin appear to pose little risk in causing depression, although rare occurrences have been reported.
Is hydralazine used for anxiety?
It can also be used to help control anxiety and produce sleep before surgery. This medicine is also used to relieve symptoms of allergic conditions (eg, chronic urticaria and atopic and contact dermatoses). Hydroxyzine is an antihistamine.
What drug can replace hydralazine?
We conclude that labetalol appears to be a safe and effective alternative to hydralazine for treating hypertension in the peripartum period, but serious rare side effects have not yet been quantified.
Does hydralazine cause fluid retention?
Hydralazine tends to increase heart rate and may cause fluid retention through its action on the kidneys. 2 These effects are usually countered when hydralazine is prescribed along with other medicines like beta-blockers and diuretics.
When should you not use hydralazine?
- kidney disease;
- systemic lupus erythematosus;
- angina (chest pain); or.
- a stroke.
What should you check before giving hydralazine?
Advise them to check BP at least weekly and report significant changes. Patients should weigh themselves twice weekly and assess feet and ankles for fluid retention. May occasionally cause drowsiness. Advise patient to avoid driving or other activities requiring alertness until response to medication is known.
What class of drug is hydralazine?
hydralazine (Rx) Brand and Other Names: Classes: Vasodilators.
Is hydralazine safe for kidneys?
This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure can decrease the risk of heart attacks and strokes.
Is hydralazine used as a water pill?
Hydralazine works by relaxing blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. The hydrochlorothiazide is a type of medicine known as a thiazide diuretic and helps reduce the amount of water in the body by acting on the kidneys to increase the flow of urine.
Does hydralazine raise blood sugar?
Thiazide diuretics may raise blood sugar levels. While you are using this medicine, be especially careful in testing for sugar in your blood or urine.
How many mg of hydralazine is too much?
Adults—At first, 10 milligrams (mg) four times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 50 mg four times a day.
Can hydralazine cause anxiety?
anxiety, muscle or joint pain, runny or stuffy nose, or. itching or skin rash.
How long does hydralazine stay in your system?
Although hydralazine starts working to lower your blood pressure in as little as 1 hour, it only stays in your body for 3 to 7 hours.
Does hydralazine cause ED?
Direct vasodilators act by relaxing smooth muscle of arterioles and sometimes veins, reducing systemic vascular resistance. Some of them, such as hydralazine and minoxidil have rarely been reported to cause ED.
Does hydralazine cause liver damage?
Introduction. Hydralazine is a commonly used oral antihypertensive agent that acts by inducing peripheral vasodilation. Hydralazine has been linked to several forms of acute liver injury as well as a lupus-like syndrome.
Can blood pressure medicine cause mental problems?
Like all medications, blood pressure drugs sometimes cause unwanted side effects. While many are mild and short-lived, some are more worrisome, including mood changes such as depression.
Is hydroxyzine like Xanax?
Hydroxyzine (Atarax, Vistaril) and alprazolam (Xanax) are two commonly prescribed anti-anxiety medications. Both medications kick in quickly and share some common side effects, such as drowsiness and dry mouth. Alprazolam — especially high doses — can be habit-forming, but hydroxyzine does not have this risk.
What are the dangers of hydroxyzine?
You might feel dizzy or faint, or you might have a fast, pounding, or uneven heartbeat. Make sure your doctor knows if you or anyone in your family has ever had a heart rhythm problem such as QT prolongation. This medicine may cause a serious skin condition called acute generalized exanthematous pustulosis (AGEP).
How does hydroxyzine make you feel?
As an antihistamine, hydroxyzine blocks the effects of histamine in your body, which makes you sleepy. (Think about how you feel after taking Benadryl or Nyquil.) Serotonin is a chemical that affects your mood. Hydroxyzine’s unique effect on serotonin is likely why it’s the only antihistamine used for anxiety.
What is the safest high blood pressure medication?
Safe medications to use include methyldopa and potentially some diuretics and beta-blockers, including labetalol.