Metabolic Abnormalities Caused by Purging Can Be Life Threatening. Purging behaviors, causing abnormalities seen with sodium, potassium, chloride, bicarbonate, most commonly disrupts electrolyte levels and overall pH levels.
Can bulimia cause metabolic acidosis?
Laxative abusers can develop severe constipation on withdrawal of laxatives, related to damage to the myenteric plexus. The typical electrolyte abnormalities associated with bulimia are hypokalemia and metabolic acidosis.
Does anorexia cause metabolic alkalosis?
In anorexia nervosa, under-nutrition and weight regulatory behaviours such as vomiting and laxative abuse can lead to a range of biochemical problems. Hypokalaemia is the most common electrolyte abnormality. Metabolic alkalosis occurs in patients who vomit or abuse diuretics and acidosis in those misusing laxatives.
Does anorexia cause acidosis or alkalosis?
Self-induced vomiting is a common feature of the eating disorders anorexia nervosa and bulimia. Because these individuals are losing HCl from stomach secretions, it is not uncommon for them to develop a metabolic alkalosis.
Does bulimia affect metabolic rate?
Resting metabolic rate, adjusted for differences in lean body mass, was significantly lower in bulimics (mean +/- SE, 4201 +/- 126 kJ/d) than healthy volunteers (4694 +/- 172 kJ/d).
What causes metabolic alkalosis?
Metabolic alkalosis is caused by too much bicarbonate in the blood. It can also occur due to certain kidney diseases. Hypochloremic alkalosis is caused by an extreme lack or loss of chloride, such as from prolonged vomiting.
What labs are abnormal with bulimia?
Endocrine studies in patients with bulimia nervosa may exhibit the following abnormal findings: Decreased follicle-stimulating hormone (FSH), leuteinizing hormone (LH), and estradiol levels. Prolactin levels: Studies have documented both increased and decreased basal serum prolactin in association with bulimia nervosa.
Which acid-base disorder would be most likely to occur in a patient with bulimia?
The most common acid-base abnormality found in bulimia nervosa is a metabolic alkalosis (bicarbonate >28 mEq/L).
When does metabolic alkalosis occur?
Metabolic alkalosis occurs when digestive issues disrupt the blood’s acid-base balance. It can also be due to conditions affecting the liver, kidneys or heart. Metabolic alkalosis is usually not life-threatening. It does not have lingering effects on your health once it is treated.
What is the primary characteristic of bulimia?
Bulimia is an eating disorder. It is characterized by uncontrolled episodes of overeating, called bingeing. This is followed by purging with methods such as vomiting or misuse of laxatives. Bingeing is eating much larger amounts of food than you would normally eat in a short period of time, usually less than 2 hours.
What does bulimia do to electrolytes?
Vomiting & Electrolytes Various side effects come along with purging behaviors. Each time you vomit, you lose fluid as well as food. You also lose the salts and electrolytes in your meals through your vomiting episodes. Both can lead to electrolyte imbalances.
Can bulimia cause electrolyte imbalance?
Bulimia is devastating disease to the mind, soul, and body; and it is in the body where regular purging creates potentially fatal electrolyte imbalances. Electrolytes are electrically charged salts, or ions, used by the body to regulate hydration and Ph levels, as well as nerve and muscle function.
Why is amylase increased in bulimia?
Conclusion. These findings provide evidence to suggest that it is recurrent binge eating involving large amounts of food, rather than self-induced vomiting, which contributes to elevated serum amylase values in BN.
Does anorexia slow metabolism?
Hypermetabolism is a phenomenon seen during the journey towards recovery from anorexia nervosa. When a person is actively restricting calories, the metabolism becomes very slow.
Do recovered anorexics need more calories?
Remember caloric needs commonly increase as weight is gained. Therefore patients recovering from anorexia nervosa commonly require escalating caloric intake in order to maintain a steady weight gain.
Does vomiting cause metabolic alkalosis?
Vomiting or nasogastric (NG) suction generates metabolic alkalosis by the loss of gastric secretions, which are rich in hydrochloric acid (HCl). Whenever a hydrogen ion is excreted, a bicarbonate ion is gained in the extracellular space.
Which of the following is the most common cause of metabolic alkalosis?
Loss of stomach acids. This is the most common cause of metabolic alkalosis. It’s usually brought on by vomiting or suction through a nose-feeding tube. The gastric juices have a high content of hydrochloric acid, a strong acid. Its loss causes an increase in the alkalinity of the blood.
What indicates metabolic alkalosis?
Normal human physiological pH is 7.35 to 7.45. A decrease in pH below this range is acidosis, an increase over this range is alkalosis. Metabolic alkalosis is defined as a disease state where the body’s pH is elevated to greater than 7.45 secondary to some metabolic process.
How does bulimia affect blood work?
Laboratory abnormalities become more common with decreasing weight and increasing severity of purging behaviors. The electrolyte levels are most likely to be affected. Hypokalemia, hypochloremia, hyperphosphatemia, and metabolic alkalosis are common, especially in lower-weight bulimics.
What is the most insignificant characteristic of a person with bulimia?
What is the most insignificant characteristic of a person with bulimia? The person is close to her ideal body weight. Bulimia nervosa is more prevalent than anorexia nervosa in both women and men. What is not a risk of being underweight?
Can blood Work detect bulimia?
There aren’t any laboratory tests to specifically diagnose bulimia. Your healthcare provider may order tests to see how bulimia has affected your health. These tests include: Blood test.
What acid base imbalance is caused by vomiting?
Metabolic alkalosis occurs when bicarbonate levels in your blood get too high or your body loses too much acid. It can be brought on by a long period of vomiting, overuse of diuretics, or an overactive adrenal gland.
Why does vomiting cause metabolic acidosis?
Vomiting causes changes in acid base balance due to loss of chloride ions from the stomach, which can lead to an increase of HCO3 in the extracellular fluid. Our patient had her first episode of CVS when she was 3 years old and each episode of CVS is associated with metabolic acidosis.
How do you fix metabolic alkalosis?
Metabolic alkalosis is corrected with the aldosterone antagonist spironolactone or with other potassium-sparing diuretics (eg, amiloride, triamterene). If the cause of primary hyperaldosteronism is an adrenal adenoma or carcinoma, surgical removal of the tumor should correct the alkalosis.
Which 4 of the following conditions could result in metabolic alkalosis?
Thus, metabolic alkalosis can only persist if the ability to excrete excess bicarbonate in the urine is impaired due to one of the following causes: hypovolemia; reduced effective arterial blood volume (due, for example, to heart failure or cirrhosis); chloride depletion; hypokalemia; reduced glomerular filtration rate …