The recommended adult initial dosage of MEGACE Oral Suspension is 800 mg/day (20 mL/day). Shake container well before using. In clinical trials evaluating different dose schedules, daily doses of 400 and 800 mg/day were found to be clinically effective.
Is megestrol used for anorexia?
Megestrol acetate (MA) is currently used to improve appetite and to increase weight in cancer‐associated anorexia. In 1993, MA was approved by the US Food and Drug Administration for the treatment of anorexia, cachexia or unexplained weight loss in patients with AIDS.
What is megestrol 40 mg used for?
Megestrol is a man-made version of the human hormone progesterone. It treats breast cancer and endometrial cancer by affecting female hormones involved in cancer growth. It increases weight gain by increasing appetite.
Can I take megestrol twice a day?
Megestrol comes as a 20 or 40 mg tablet, or as an oral suspension. It is usually taken once or twice a day. Since each person responds differently to medical treatments, your doctor will recommend the dose and duration of therapy that is best for you.
What are the doses for Megace?
The recommended adult initial dosage of Megace® ES oral suspension is 625 mg/day (5 mL/day or one teaspoon daily).
How long does it take for megestrol to increase appetite?
It may take up to 3 weeks to first notice an improved appetite. It may take up to 12 weeks to notice weight gain. This medicine can cause birth defects. Do not get pregnant while taking this drug.
How long can you take megestrol?
Conclusions: A substantial proportion of patients continue to use megestrol acetate for periods of up to 3 years or longer with continued control of hot flashes. This treatment appears to be relatively well tolerated.
Does Megace increase appetite?
Administration of MA results in substantial increases in appetite and body weight in patients with HIV-associated wasting and in those with cancer (1). MA is currently Food and Drug Administration (FDA) approved for HIV-associated weight loss.
How safe is megestrol?
Megestrol acetate (MA) is neither safe nor effective for stimulating appetite in malnourished nursing home residents.
What happens if you take too much megestrol?
Get medical help right away if you have any very serious side effects, including: symptoms of a blood clot (such as chest pain, trouble breathing, pain/redness/swelling of arms or legs), confusion, mental/mood changes, weakness/numbness on one side of the body, trouble speaking, vision changes.
How often do you take megestrol?
You usually take megestrol acetate once a day, at the same time each day. But sometimes the dose is divided up, so that you take the tablets a couple of times a day. When you start taking it you should take them for at least 2 months.
Does megestrol make you gain weight?
Although the precise mechanism by which megestrol acetate exerts its effect remains unclear, weight gain was observed in 75% of patients in the high-dose study and in nearly all of those who remained on therapy for 6 weeks.
How long does it take megestrol acetate to start working?
Patients will typically improve their appetite within the first few weeks after starting the drug. Weight gain, often in the form of fat, may take longer. Resistance exercise traing coupled with the weight gain may lead to improved lean muscle mass. A typical treatment duration may be 12 weeks.
What are the side effects of megestrol 40 mg?
- Blurred vision.
- flushed, dry skin.
- fruit-like breath odor.
- increased thirst.
- increased urination.
- slow or fast heartbeat.
- stomach pain.
- unexplained weight loss.
How is megestrol prescribed?
What is the dosage for megestrol? The recommended dose for stimulating appetite is 800 mg per day of the regular megestrol suspension (40 mg/ml) or 625 mg per day of the ES formulation (125 mg/ml). Breast cancer is treated with 40 mg four times daily.
What is Megace 40mg?
Megestrol is used to treat loss of appetite and weight loss in people with AIDS. Improving your appetite and gaining weight may help you feel better and be more active. Megestrol is similar to a natural substance made by the body called progesterone.
What are the long term side effects of megestrol?
- Changes in appetite.
- Decreased sexual ability/desire.
- Gas (flatulence)
- High blood pressure (hypertension)
- Hot sweats.
Does Megace cause blood clots?
Megestrol can increase the risk of blood clots and heart attack. If you experience symptoms of these problems, you should contact your healthcare provider immediately or go to an emergency room.
Does megestrol make you tired?
You may feel tired and lacking energy when having megestrol. Take it easy if you feel tired. Try to strike a balance between periods of rest and some physical activity. Some people feel nauseous, especially during the first weeks after starting to take megestrol.
Why is Megace hazardous?
Overexposure to megestrol acetate, the active ingredient, may affect the developing fetus and impair fertility. Repeated overexposure may cause an increased risk of cancer based on the results of animal studies. Avoid skin contact, eye contact, and inhalation.
Does megestrol cause depression?
This medicine may cause adrenal gland problems. Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting. This medicine may cause diabetes.
Who should not take Megace?
high blood pressure. chronic heart failure. obstruction of a blood vessel by a blood clot. pregnancy.
How do I stop taking megestrol?
Special instructions for megestrol acetate Do not stop taking this medicine until your doctor tells you to do so. If you have taken this medicine for more than a year, you should slowly decrease the dose over a period of 2 to 3 weeks before you stop taking it.
Is megestrol a stimulant?
Megestrol acetate is an oral synthetic progesterone used since the early 1990s as an appetite stimulant. Weight gain tends to be associated with increase in body fat rather than muscle.
What do you eat when you have no appetite?
- Rice pudding.
- Shepherd’s pie.
- Scrambled eggs.
- Tuna salad.
- Split pea soup.
- Biscuits and gravy.
- Oatmeal with banana.
- Peanut butter and jelly on white bread.