Megestrol acetate (MA) is currently used to improve appetite and to increase weight in cancer‐associated anorexia. In 1993, MA was approved by the US Food and Drug Administration for the treatment of anorexia, cachexia or unexplained weight loss in patients with AIDS.
Does Megace increase appetite?
MEGESTROL (me JES trol) suspension improves appetite and helps cause weight gain. It is used in conditions that cause significant loss of appetite and weight, such as AIDS. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
Can Megace tablets be used for appetite?
USES: Megestrol is used to treat loss of appetite and weight loss in people with AIDS.
Does Megace cause weight gain?
Weight gain as a result of increase in food intake is a common side effect of megestrol acetate, which is why it sometimes used to treat cachexia (muscle and weight loss or wasting and anorexia associated with cancer). This may be managed through dietary changes and exercise.
Who should not take megestrol?
You should not use megestrol if you are allergic to it, or if you are pregnant. Tell your doctor if you have ever had: diabetes; an adrenal gland disorder; or.
How safe is megestrol?
Megestrol acetate (MA) is neither safe nor effective for stimulating appetite in malnourished nursing home residents.
How long can you stay on Megace?
Conclusions: A substantial proportion of patients continue to use megestrol acetate for periods of up to 3 years or longer with continued control of hot flashes. This treatment appears to be relatively well tolerated.
How fast does Megace work for appetite?
Patients will typically improve their appetite within the first few weeks after starting the drug. Weight gain, often in the form of fat, may take longer. Resistance exercise traing coupled with the weight gain may lead to improved lean muscle mass. A typical treatment duration may be 12 weeks.
Why is Megace hazardous?
Overexposure to megestrol acetate, the active ingredient, may affect the developing fetus and impair fertility. Repeated overexposure may cause an increased risk of cancer based on the results of animal studies. Avoid skin contact, eye contact, and inhalation.
What are the side effects of Megace?
- Trouble sleeping, fever, gas, decreased sexual ability/desire, weight gain, changes in appetite, or upset stomach may occur.
- Tell your doctor right away if you have any serious side effects, including: fast/pounding heartbeat, fatigue, headache, swelling of the hands/feet.
What are the long term side effects of megestrol?
- Deep vein thrombosis (DVT)
- Pulmonary embolism.
- Adrenal insufficiency.
What are the side effects of taking megestrol?
- Blurred vision.
- flushed, dry skin.
- fruit-like breath odor.
- increased thirst.
- increased urination.
- slow or fast heartbeat.
- stomach pain.
- unexplained weight loss.
Does Megace make you sleepy?
you might feel tired, weak or lacking energy. hair loss or thinning. skin rash.
Is megestrol good for appetite?
Megestrol suspension is used to treat loss of appetite, malnutrition, and severe weight loss in patients with acquired immunodeficiency syndrome (AIDS). Megestrol should not be used to prevent loss of appetite and severe weight loss in patients who have not yet developed this condition.
Does megestrol cause depression?
This medicine may cause adrenal gland problems. Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting. This medicine may cause diabetes.
What happens when you stop taking megestrol?
Your appetite will return to normal when you stop taking megestrol. Blood clots may rarely occur. This is more likely to happen if you have had blood clots before. Signs to watch for include tenderness or hardness over a vein, calf tenderness, sudden onset of cough, chest pain, or shortness of breath.
Does megestrol acetate make you tired?
You may feel tired and lacking energy when having megestrol. Take it easy if you feel tired. Try to strike a balance between periods of rest and some physical activity. Some people feel nauseous, especially during the first weeks after starting to take megestrol.
Should megestrol be taken with or without food?
Megestrol can be taken with or without food. The oral suspension bottle should be well shaken before each dose.
What drug class is Megace?
Megace may be used alone or with other medications. Megace belongs to a class of drugs called Antineoplastics, Hormones; Progestins; Appetite Stimulants.
What is megestrol 40 mg used for?
Megestrol is used to treat loss of appetite and weight loss in people with AIDS. Improving your appetite and gaining weight may help you feel better and be more active. Megestrol is similar to a natural substance made by the body called progesterone.
How much Megace should I take?
Typical dosing for megestrol Breast cancer: The typical dose is 40 mg by mouth four times a day. Endometrial cancer: The typical dose ranges from 40 mg to 320 mg by mouth per day, split up into several doses throughout the day.
Does Megace come in pill form?
Megace is supplied as tablets for oral administration containing 20 mg and 40 mg megestrol acetate.
Is Megace a steroid?
Chemistry. MGA, also known as 17α-acetoxy-6-dehydro-6-methylprogesterone or as 17α-acetoxy-6-methylpregna-4,6-diene-3,20-dione, is a synthetic pregnane steroid and a derivative of progesterone.
How much weight do you gain on megestrol?
At the end of the 12-week period during which the participants received the study drug, those in the megestrol acetate group showed a mean weight gain of 2 lb, 3 oz ± 2 lb, 2 oz (1.05 ± 1.0 kg) compared with 2 lb ± 1 lb, 5 oz (0.91 ± 0.68 kg) in the placebo group.
Does Megace cause diarrhea?
SIDE EFFECTS: This medication can cause weight gain, changes in appetite, stomach upset, diarrhea, gas, trouble sleeping, decreased sexual ability/desire, or fever. Women may experience changes in their menstrual periods, including unpredictable bleeding.