Why is bupropion contraindicated in bulimia?


Sharing is Caring


Bupropion is contraindicated because of the increased risk for seizures; patients should also be warned against its use for smoking cessation. Finally, drugs that can increase appetite or cause weight gain (e.g., olanzapine, mirtazapine, paroxetine) are not recommended.

Does CONTRAVE work for binge eating?

The benefit of using Contrave (the combination of Wellbutrin PLUS naltrexone) is that Wellbutrin can reduce the number of binge eating episodes while naltrexone works to reduce the hormone imbalances caused by previous binging.

What is the best antidepressant for bulimia?

The antidepressants that are most commonly used to reduce the binge-purge cycle associated with bulimia is Prozac (aka Fluoxetine). Prozac is a selective serotonin reuptake inhibitor (SSRI). Prozac has proven to reduce binge-purge cycles in bulimia.

Does CONTRAVE speed up metabolism?

How Contrave Works. Contrave stimulates the hunger and reward center of the brain. It raises levels of dopamine to reduce hunger and control cravings. Contrave doesn’t affect the metabolism, so it’s safe to use in people with heart disease.

What should you not take with CONTRAVE?

Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication.

How does Contrave make you lose weight?

Contrave is an FDA-approved weight loss pill meant to be used with a healthy diet and exercise for weight management. This drug works as an appetite suppressant, and it reduces cravings.

Does bupropion help with food cravings?

Bupropion was well tolerated and produced significantly greater โ€“ albeit quite modest โ€“ short-term weight loss in overweight and obese women with BED. Bupropion did not improve binge eating, food craving, or associated eating disorder features or depression relative to placebo.

Can you take Wellbutrin if you are bulimic?

Bupropion/naltrexone should be avoided in patients with uncontrolled hypertension, history of seizures, or if there is a recent history of bulimia or anorexia nervosa.

How fast is weight loss on Wellbutrin?

Bupropion seems to be effective for weight-loss maintenance as well. A 2012 study found that obese adults who took bupropion SR (standard release) in 300mg or 400mg doses lost 7.2% and 10% of their body weight, respectively, over 24 weeks and maintained that weight loss at 48 weeks (Anderson, 2012).

Can your body recover from bulimia?

Eating disorders damage nearly every system in the body, but people living with even the most extreme forms of anorexia or bulimia can recover with treatment.

What drug is FDA approved for bulimia?

Article highlights. Medications for the maintenance of eating disorders, bulimia nervosa (BN) and binge eating disorder (BED), are limited. Fluoxetine for BN and lisdexamfetamine for BED are the only FDA-approved medications.

Why does Prozac treat bulimia?

The imbalance of serotonin levels in the body can increase urges to binge and purge in women and men who have bulimia, and antidepressant medications can decrease these urges by effectively balancing the levels of neurotransmitters in the brain.

Which drug has been used to help reduce binges and vomiting in persons with bulimia nervosa?

Ondansetron (Zofranยฎ, GlaxoSmithKline) (24mg/day), an anti-emetic medication, is also reported to reduce binge eating and self-induced vomiting in a small placebo-controlled study of 29 patients with bulimia nervosa.

How quickly do you lose weight on Contrave?

You can start to see weight loss as soon as 4 weeks after you start taking Contrave (naltrexone / bupropion). However, the medication can cause serious side effects, such as unusual changes in your behavior, suicidal thoughts and actions, and seizures.

How much weight do people lose on Contrave?

How much weight can you lose with Contrave? Contrave can help people lose a significant amount of weight, but only when it’s taken properly and combined with a healthy diet and exercise. Clinical trial data showed that study participants lost 5% to 15% of their body weight while taking Contrave.

Can you drink caffeine with Contrave?

Side effects such as nervousness, irritability, difficulty with sleep, increased blood pressure, tremor, or seizures may get worse if you take Bupropion and an excessive amount of caffeine. Try to limit Caffeine intake during Bupropion use.

Is Contrave good for anxiety?

Changes in mood or behavior: Contrave can cause worsening depression, as well as anxiety, panic attacks, trouble sleeping, agitation, and thoughts about suicide or self-harm. It can also cause thoughts of homicide.

Does Contrave increase energy?

Therefore, the contrave fixed-combination of bupropion SR and naltrexone SR exerts a synergistic effect on reducing appetite and increasing energy expen- diture [9].

How does Contrave make you feel?

Contrave can also cause increased blood pressure, anxiety, and insomnia. Other side effects include constipation and dizziness. See our Drug Facts Box (PDF) for the full analysis of the prescription weight loss pill Contrave.

Does Contrave work immediately?

How quickly can patients expect to lose weight? In 3 clinical trials, there was significantly greater weight loss observed in patients using CONTRAVE compared to those on diet and exercise alone at the first time point assessed, which was 4 weeks after the initiation of therapy.

Is Contrave a stimulant?

Learn About CONTRAVE And unlike other weight-loss medications, CONTRAVE is not a controlled substance, scheduled drug, or stimulant.

Can you stop Contrave cold turkey?

If you are thinking about discontinuing your Wellbutrin treatment, talk to your doctor about gradually tapering off your dose over time. Bupropion should never be stopped cold turkey unless your doctor instructs you to do so.

How does bupropion affect eating disorders?

Conclusions: Bupropion was well tolerated and produced significantly greater-albeit quite modest-short-term weight loss in overweight and obese women with BED. Bupropion did not improve binge eating, food craving, or associated eating disorder features or depression relative to placebo.

Should I take Wellbutrin if I have an eating disorder?

You should not take Wellbutrin if you currently have, or formerly had, an eating disorder. For some reason, people with a history of anorexia nervosa or bulimia seem to be more likely to experience Wellbutrin-related seizures.

Does Wellbutrin speed up metabolism?

Wellbutrin basically acts to increase the amount of adrenaline (norepinephrine) at the neurotransmitter synapse and it is likely through this influence that it helps modulate appetite and increase metabolism leading to weight loss.

Craving More Content?

Eating Disorder Resources